The book serves as a brief but pointed introduction to the subject, with emphasis on the practical details. Some attempt is made to integrate column chromatography into the discussion, but that subject is an unwelcome intruder. The methods described in the book includes separations of amino acids and many of their derivatives, other nitrogenous compounds such as indoles and imidazoles, purine and pyrimidine derivatives, sugars, steroids, drugs, and many other categories of compounds. Free radicals and other reactive species can cause oxidative damage to biomolecules when oxidant species exceed the antioxidant defences in the body, resulting in oxidative stress. Oxidatively damaged products have been associated with aging as well as with the development of pathologies like cancer, cardiovascular disease, neurodegenerative disorders, diabetes, inflammation, etc. Reliable measurements of biomarkers of oxidative damage to macromolecules would afford information on the predisposition and prognosis of certain pathologies, being of utmost importance in evaluation of the effect of intervention with antioxidants on the incidence of diseases associated to oxidative stress. It is intended that this unique reference will prove to be an essential resource to the students and researchers of physics, exploring chromatographic and electrophoretic techniques.
AUTOR: Bidhendi, Hoveidi J.
EDITORA: Auris Reference
DISPONIBILIDADE DO PRODUTO: Sob Encomenda - Até 40 dias ( Importação )